tag:blogger.com,1999:blog-3492197469143963742.post5761660970019119784..comments2023-06-13T04:45:22.434-04:00Comments on Infection Landscapes: Malaria Part 4: The LandscapeMichael Walshhttp://www.blogger.com/profile/05038031388622939797noreply@blogger.comBlogger10125tag:blogger.com,1999:blog-3492197469143963742.post-16197115021252148732016-04-22T15:07:09.944-04:002016-04-22T15:07:09.944-04:00Shmuel, you make an interesting point that though ...Shmuel, you make an interesting point that though it seems intuitive for people to avoid open pools of water. I think this would be very difficult to achieve, particularly in developing countries where malaria is endemic. Without the proper infrastructure it would be unlikely that people would be able to avoid all mosquito breeding grounds. The best prevention efforts would still likely be distribution of malaria drugs. Christine Leehttps://www.blogger.com/profile/08026286087487756149noreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-69710474639000546592016-04-15T12:37:35.614-04:002016-04-15T12:37:35.614-04:00i found it interesting that although the vector fo...i found it interesting that although the vector for Malaria does not move very far in its lifetime, it is able to adapt very well to the changing lifestyles of humans. The urbanization of the population made it even easier for the vector to breed all the while making it more difficult for the human population to control it. while human movement and man made water systems, such as canals for agriculture has made great breeding grounds for the vector, with urbanization, there are so many small and efficient breeding grounds for continued transmission. avoiding open pools of water seems like a simple initiative, yet it doesn't seems simple enough to avoid the enormous spread of malariaShmuelhttps://www.blogger.com/profile/16321894818345397249noreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-2623334719434573922015-10-26T23:24:21.219-04:002015-10-26T23:24:21.219-04:00http://nyti.ms/1kAKBon
I don't know if eradic...http://nyti.ms/1kAKBon<br /><br />I don't know if eradicating the disease in the US (and most of developed countries) decades ago caused the lack of urgency to develop a malaria vaccine. <br />The article above is about the mixed reviews for the newly developed vaccine and the worry about who is going to pay for a pilot program which would take another 5 years. Anonymoushttps://www.blogger.com/profile/01959289654941672974noreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-12620236076463313762015-07-24T14:40:26.580-04:002015-07-24T14:40:26.580-04:00Yet another hope and breakthrough in public health...Yet another hope and breakthrough in public health, global health and infectious diseases, as the fear of emerging resistance to the most potent anti-malarial medication artemisinin spread in Burma and India, a new drug that tackles all the stages of malaria parasite life cycle and can probably decrease transmission as well is in its final stages of clinical trials.<br /><br />#Please see link for article June/17/2015<br /><br />http://www.theguardian.com/science/2015/jun/17/new-anti-malarial-treatment-battle-against-drug-resistancAnonymoushttps://www.blogger.com/profile/16420001543069750611noreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-2951883504939208232015-07-14T18:17:15.406-04:002015-07-14T18:17:15.406-04:00I thought it was interesting that, despite malaria...I thought it was interesting that, despite malaria not being endemic to the US, that an estimated 1500 cases are diagnosed here each year. That led me to dig a bit deeper into how malaria was eradicated here. I was surprised to find out that it was considered to be eliminated over 65 years ago. Eradication efforts began in 1947, headed by the National Malaria Eradication Program (participants were state and local health agencies and the CDC). At that time over 15,000 cases of malaria were reported each year. By 1950, that number had dropped over 80% to 2,000 cases, and by 1951 it was considered completely eradicated. Pretty impressive results in just 4 year time span. Danielle Dhttps://www.blogger.com/profile/02425656730312985413noreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-62750523827645849522014-11-14T16:54:54.567-05:002014-11-14T16:54:54.567-05:00thanks blue moon for pointing out that infrastruct...thanks blue moon for pointing out that infrastructural projects are essential element of fighting malaria. Since India is one of the most stricken areas of the world with diseases that is caused by mosquitos, including malaria, dengue, ..etc<br />I wonder what will be the effect of the indian government's new commitment and campaign to improve health and sanitation on all these diseases, since improving sanitation will remove a lot of the habitat of the mosquitos and what that will lead india to, and also if successful can it be copied in other areas of the world.Usama Wissanoreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-47716241282560179722014-11-14T16:46:47.543-05:002014-11-14T16:46:47.543-05:00Although most malaria vector control has been cent...Although most malaria vector control has been centered on taking advantage of the plasmodium falciparum life cycle, the responsibility of vector control should take a multifaceted approach and involve individuals and community interventions. With regions where malaria is highly prevalent, there has been deforestation, urbanization and exponential population growth, which has provided the appropriate environmental factors for disease transmission as well as consistent maintenance of the parasite lifecycle and host reservoir. Malaria is extremely difficult to control due to the complex life cycle and interactions by the parasite.Hariprasad Raohttps://www.blogger.com/profile/12186696543612891924noreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-15588480611318209592013-11-15T15:18:57.682-05:002013-11-15T15:18:57.682-05:00Even with that being said, leaving vector control ...Even with that being said, leaving vector control to the responsibility of the individual, I feel, will not significant impact the spread of malaria. From my understanding, malaria is hyperlocal which is the point I think you are dwelling on. However, the actual impact of malaria is so wide across SSA and other endemic areas of the world, that watching for cans or containers of stagnant water in urban areas simply would not do much for the disease as a whole. I know that for the tsetse fly, they used the sterile insect technique to reduce the burden of disease and that fly population affecting humans and animals. Since this is probably costly, I know this can't be advocated for the anopheles mosquito given the widespread distribution of malaria. I do wonder though, could this be implemented in areas that have endemicity and are urbanized? I would assume that cities could more realistically push for this than rural areas and poor villages. The best question would be if this technique could be applied to anopheles and could there be some public health campaign reducing the cost that would be tied into this kind of eradication?Marc S.https://www.blogger.com/profile/03980040361920520595noreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-49651452670343388142013-11-15T00:01:44.662-05:002013-11-15T00:01:44.662-05:00In response to the previous post:
Based on malaria...In response to the previous post:<br />Based on malaria prevention and control program, infrastructure projects are an essential element of development and can contribute to the long-term health and well being of beneficiaries.Most infrastructure projects undertaken in malaria endemic areas can be expected to adversely affect malaria transmission and disease but in most cases, that effect can be reduced by careful analysis and design. Infrastructure projects can exacerbate malaria risk if they have components that include construction of roads, dams, irrigation schemes, pipelines, water supplies and new or upgraded residential sites. It is in the government, corporations and local people's interest to expand existing environmental assessment tools to include an assessment of malaria consequences, and to develop a process by which personnel can access environmental health professionals to assist in developing mitigation plans. <br />About maIaria vaccine, recent Phase III clinical trials, the RTS,S malaria vaccine had lower-than-desired efficacy, but the data demonstrated that it is possible to vaccinate against a parasite.<br />Indoor residual spraying and long-lasting insecticide-treated bed nets are currently the two most effective interventions for reducing and interrupting malaria transmission. Unfortunately, their effectiveness is threatened by increasing mosquito resistance to the pesticides used. Moreover, indoor sprays and bed nets are not effective against mosquito species that are active outside homes or that bite during the daylight hours.blue moonhttp://bluemoonwithpeace.blogspot.ca/noreply@blogger.comtag:blogger.com,1999:blog-3492197469143963742.post-55343986359082470982011-12-02T22:04:50.177-05:002011-12-02T22:04:50.177-05:00After reading the post I have a great understandin...After reading the post I have a great understanding of the overarching landscape of malaria. The most interesting component is the ecotones, those transitional sites that change the entire ecology, which have historically been beneficial to the proliferation of the anopheles mosquito. <br />Because farmland is so engrained into life in SSA, and there is qidespread deforestation the possibility of bringing mosquitoes back into the forest is unthinkable. <br />what can be done to prevent urbanization as being an add on to the diseases growth is identification and control of possible breeding sites. if you see a puddle, get a broom and break it up or no cans of water without a cover...george koutsnoreply@blogger.com